Goodpasture's Disease: A Case of Rapidly Progressive Kidney Injury in an Elderly Patient

Authors

Imane ELABOUDY, Mohamed Reda EL FAROUKI, Saida EL ASRI, Jamal Eddine NAJI, Mohamed EL HASSANI

Journal Information

Journal: Medpeer Publisher

ISSN: 3066-2737

Volume: 2

Issue: 5

Date of Publication: 2025/05/06

DOI: 10.70780/medpeer.000QGNG

Abstract

Goodpasture's disease, a rare and aggressive autoimmune pathology, manifests with renal and/or pulmonary involvement due to the production of anti-glomerular basement membrane autoantibodies. We report the case of an 88-year-old patient presenting with rapidly progressive acute kidney injury associated with a history of chronic rhinitis, bronchitis, and an episode of hemoptysis, in whom the diagnosis of Goodpasture's disease was confirmed. Therapeutic management was limited by the unavailability of plasmapheresis in our department, highlighting the diagnostic and therapeutic challenges of this pathology in elderly patients. The clinical course was marked by the need for chronic hemodialysis.

Keywords

Goodpasture's Disease, Rapidly Progressive Glomerulonephritis (RPGN), Geriatric Nephrology, Plasmapheresis