Mamadou.Chérif. KANTE, A. ZEGMOUT, S. EL FATHI, M. MZOURI, H. SOUHI H. EL OUAZZANI, I. ABDERAHMAN-RHORFI
Journal: Medpeer Publisher
ISSN: 3066-2737
Volume: 3
Issue: 9
Date of Publication: 2026/09/05
Resumé :
La tuberculose est une maladie infectieuse d’origine bactérienne, transmise par voie aérienne. Elle est causée principalement par le Bacille de Koch (M. tuberculosis), mais aussi par M. africanum et M. bovis. Ces bactéries aérobies à croissance lente représentent un problème majeur de santé publique dans le monde.
Le bilan biologique est utile non seulement pour le pronostic et le suivi thérapeutique, mais parfois aussi pour le diagnostic de la tuberculose. Il met en évidence des anomalies de l’hémogramme et des comorbidités fréquentes, dont la prise en charge simultanée est nécessaire
Summary
Tuberculosis is an infectious disease of bacterial origin that is transmitted via the airborne route. It is caused primarily by the Koch bacillus (*M. tuberculosis*), but also by *M. africanum* and *M. bovis*. These slow-growing aerobic bacteria represent a major global public health problem.
Laboratory testing is useful not only for prognosis and monitoring treatment, but sometimes also for diagnosing tuberculosis. It reveals abnormalities in the complete blood count as well as common comorbidities that require simultaneous management.
Materials and Methods: This retrospective study examined biological abnormalities associated with tuberculosis at the Pulmonology Department of the Mohamed V Military Teaching Hospital in Rabat (HMIMV) over a six-month period between July 2025 and December 2025.
Results: The results showed a male predominance (75%) and a mean age of 41 years, with pulmonary tuberculosis being the predominant form (90%). Frequent biological abnormalities included anemia (71%) and lymphopenia (70%), reflecting significant immunosuppression. Leukocytosis (50%) and thrombocytosis (25%) indicated inflammatory activation, while hyponatremia (78%) and elevated CRP (60%) served as biochemical markers of severity.
Conclusion: The integration of modern biomarkers—such as CRP, NLR, IFN-γ, or hepcidin—into clinical practice paves the way for more precise risk stratification and more personalized therapeutic monitoring.
While anti-tuberculosis treatment remains effective, careful biological monitoring is essential to optimize the management of tuberculosis patients and improve their prognosis.
Tuberculose, Anomalies Biologiques, Anémie, Lymphopénie, Thrombocytose, Probleme de santé publique
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