Sara HDIYE, Chaimae HDIYE, Sanaa BERRAG, Tarik ADIOUI, Fouad NEJJARI, Mohamed Amine ESSAOUDI, Mouna TAMZAOURTE
Journal: Medpeer Publisher
ISSN: 3066-2737
Volume: 3
Issue: 5
Date of Publication: 2026/05/21
Burkitt lymphoma is a highly aggressive B-cell non-Hodgkin lymphoma characterized by rapid proliferation and frequent abdominal involvement in its sporadic form. Primary gastric localization is extremely rare and may mimic more common gastric malignancies. We report the case of a 22-year-old male presenting with abdominal pain and an epigastric mass. Imaging revealed an antral gastric tumor with regional lymphadenopathy and splenomegaly. Endoscopy showed a circumferential ulcerative infiltrative lesion causing luminal narrowing. Histopathological examination confirmed Burkitt lymphoma with a characteristic immunophenotype and a Ki67 proliferation index of 98%. PET/CT demonstrated intense metabolic activity in the antropyloric region with nodal and splenic involvement. This case highlights the diagnostic challenge of gastric Burkitt lymphoma and the importance of early histological confirmation in young patients with gastric masses.
Burkitt lymphoma, Primary gastric lymphoma, Epigastric mass, Case report
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