Prenatal cardiac rhabdomyomas as the first manifestation of tuberous sclerosis complex: A case report

Authors

Salma El Aouadi, Rania Benkaddour, Sarah Loubaris, Kenza Bentalha, Nazik Allali, Rim Laaboudi, Fatima El Hassouni, Latifa Chat, Siham El Haddad

Journal Information

Journal: Medpeer Publisher

ISSN: 3066-2737

Volume: 3

Issue: 4

Date of Publication: 2026/04/24

DOI: 10.70780/medpeer.000QGSC

Abstract

Fetal cardiac masses are rare findings, and rhabdomyomas represent the most frequent type, with a strong association with tuberous sclerosis complex (TSC). Their prenatal detection is therefore an important indicator requiring targeted postnatal assessment. We report a case in which routine antenatal ultrasound revealed multiple cardiac rhabdomyomas, confirmed on fetal MRI. After term delivery and a normal initial examination, postnatal neuroimaging identified subependymal nodules and cortical tubers consistent with TSC, later confirmed by a pathogenic TSC2 mutation. This case illustrates the value of recognizing fetal cardiac rhabdomyomas as an early marker of TSC and the importance of timely multidisciplinary follow-up.

Keywords

Fetal cardiac tumor, Cardiac rhabdomyoma, Prenatal diagnosis, Tuberous sclerosis complex.