ATTAR MOHAMED, KIBBOU MOSTAFA, DRISS KARTITE, SINAA MOHAMED, MENFAA MOHAMED, ENNOUHI MOHAMED AMINE
Journal: Medpeer Publisher
ISSN: 3066-2737
Volume: 3
Issue: 3
Date of Publication: 2026/03/30
Dermatofibrosarcoma protuberanta (DFSP), or Darier-Ferrand tumor, is a rare, intermediate-grade skin tumor characterized by slow but locally aggressive growth [1] We report the case of a 50-year-old woman with a subcutaneous mass in the gluteal cleft that had been present for five years. The patient received six months of neoadjuvant imatinib treatment, resulting in a significant reduction in tumor volume, before undergoing wide surgical excision. Pelvic MRI showed a subcutaneous lesion without invasion of deeper tissues, associated with bilateral iliac lymphadenopathy. The diagnosis was confirmed by histopathological and immunohistochemical analysis. This case illustrates the value of a multidisciplinary approach combining medical treatment and surgery in the management of locally advanced subgluteal cleft lymphomas.
Keywords :Perianal dermatofibrosarcoma – Darier and Ferrand tumor – Imatinib – excision recurrence_ radiotherapy.
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