Facial Angioedema Induced by Paraphenylenediamine in Black Henna : A Case Report

Authors

Boubekri Ayoub, Rida Touab, Walid Atmani, Bensghir Mustapha, Drissi Mohamed

Journal Information

Journal: Medpeer Publisher

ISSN: 3066-2737

Volume: 3

Issue: 3

Date of Publication: 2026/03/27

DOI: 10.70780/medpeer.000QGRY

Abstract

Angioedema is a potentially serious hypersensitivity reaction that may be life-threatening. Paraphenylenediamine (PPD), a common component of black henna, is a potent sensitizer responsible for various cutaneous reactions. We report the case of a 21-year-old patient who developed isolated facial angioedema following first-time use of black henna. The clinical course was favorable with systemic corticosteroids and antihistamines. This case highlights the importance of early recognition to avoid diagnostic errors and optimize therapeutic management.

Keywords

Angioedema, Black henna, Paraphenylenediamine, Hypersensitivity, Facial edema