MOHAMMED YASSINE ALAMI, RABII BAHRAOUY, MOURAD BELAOUNI, LHOUSSAINE LOUZI, MOHAMMED SBITI
Journal: Medpeer Publisher
ISSN: 3066-2737
Volume: 2
Issue: 1
Date of Publication: 2025/01/31
Neonatal infections are a real public health problem and represent a constant challenge in neonatal units. Their medical and economic consequences justify welldefined surveillance and prevention measures. In order to define the circumstances of their occurrence, as well as the modalities of diagnosis and treatment, we conducted this retrospective study of 280 newborns hospitalized for suspected neonatal infection in the mother-child hospital -Pagnon-of Meknes.Infectious history was positive in 143 newborns (51%), clinical manifestations were dominated by respiratory signs (52%), as well as neurological signs (40%) and thermal disorders (18%) The hemogram showed abnormalities in 22.26% of cases, hyperleukocytosis was present in 12.14%, leukopenia in 3.92%, thrombocytopenia in 13.92% and anemia in 10.71%. The initial C-reactive protein (CRP) was positive in 52.14% of cases, the procalcitonin was positive in 22% of cases. Lumbar puncture was positive in 9% of cases. While blood culture was not realized in our study. The association: Cephalosporin of 3rd generation (C3G) and gentamicin was administered in 1st intention, in 74.28% of the patients, however the association: Cephalosporin of 3rd generation, gentamicin and ampicillin in 22.85% of the patients. The evolution was judged clinically favorable in 63% of cases, on the other hand 20% of patients had sequels, the mortality rate was 15%.The diagnosis of neonatal infection is based on anamnestic, clinical, biological and bacteriological arguments. Since antibiotic therapy is the key to management, prevention involves rigorous surveillance of pregnancies, screening of pregnant women for GBS, and medicalization of deliveries to reduce the rate of neonatal infections.
Neonatal infection , Biological markers , Bacteriology, Antibiotics , Prevention
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